Ethereum Co-Founder's Sovereign AI Future | Anthony Di Iorio, CEO & Founder of Decentral

In this episode of The Jess Larsen Show on Innovation & Leadership, Jess sits down with Anthony Di Iorio, co-founder of Ethereum and one of the earliest builders in the crypto ecosystem, for a wide-ranging conversation on Bitcoin, Ethereum, AI, decentralization, and personal sovereignty. Anthony shares how he first discovered Bitcoin in 2012, bought in when it was under $10, and helped build the Toronto Bitcoin community where he eventually met Vitalik Buterin and became part of Ethereum’s founding story.
The conversation moves beyond crypto into Anthony’s deeper mission: helping people regain control of their digital lives. He explains why Ethereum’s real breakthrough was not speculation, but utility, smart contracts, programmable systems, and the removal of unnecessary middlemen. Anthony also shares why he believes too much of today’s digital infrastructure depends on centralized platforms, cloud providers, and business models that extract value from users instead of empowering them.
Jess and Anthony dive into his newest work around AI, cognitive sovereignty, and what it could mean for one person or a tiny team to accomplish what used to require hundreds of people. Anthony introduces the ideas behind As You Wish, his AI command platform built around “genies,” and Andiami, his effort to give people tools to run their own nodes, own their data, and reduce reliance on big tech infrastructure.
This episode is a fascinating look at the next chapter of decentralization, where crypto, AI, personal computing, and human freedom all collide. If you care about the future of entrepreneurship, digital ownership, or staying in control of your own intelligence in an AI-driven world, this conversation is one to watch.
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